Leading directions of research carried out in our Department
- Development and improvement of analytical procedures for isolating, identifying and determining the quantitative composition of organic compounds contaminating the human environment, their metabolites and products of free radical modification of biomolecules
- Biological monitoring of selected xenobiotics
- Monitoring of selected toxic organic micropollutants in natural waters of Upper Silesia
- Determination of carcinogenic organic compounds in thermally processed food samples
- Development of new, sensitive and specific markers for assessing the intensity of free radical modification of lipoproteins
- Advancement of analytical methods for determining biomarkers of environmental exposure and immunological aspects
in the pathogenesis of lifestyle diseases (neurodegenerative, neurodevelopmental cancers, psoriasis, systemic lupus erythematosus)
The most important achievements
- Development of a methodology for the determination of phthalates in water using SPME microextraction and GC-MS in cooperation with the Center for Environmental Resarch Leipzig-Halle Ltd, Dep. of Analytical Chemistry, Leipzig, Germany
- Synthesis of a new C30 stationary phase and its application in liquid chromatography (for the analysis of tocopherols and carotenoids)
in cooperation with the University of Tubingen, Spectroscopy and Chromatography Laboratory of the Institute of Organic Chemistry - Development of new and development and improvement of already used procedures for determining selected biomarkers, enabling the assessment of the degree of exposure to xenobiotics occurring in polluted air and tobacco smoke and other environmental elements
- Development of an original method for determining the main metabolites of nicotine, i.e. cotinine and trans 3'-hydroxycotinine in urine
- As part of the research project funded by the Committee for Scientific Research (KBN), comprehensive methodology development for the extraction and qualitative-quantitative analysis of four classes of carcinogenic organic compounds (aminoazarenes, azarenes, polycyclic aromatic hydrocarbons, oxycholesterols) formed in high-protein food during its thermal preparation
- Development of new, sensitive and specific markers for assessing the intensity of free radical modifications of lipoproteins
- Development of methods for determining the parameters of the antioxidant protective barrier and assessing the balance of redox processes in organisms